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The French writers have named it, af er its univocal lesion, disseminated ultimate sclerosis of the brain A chronic disease of the brain and spinal cord, at times of abrupt onset, but commonly of sloio approach; in one or both legs, which extends to the arms, and passes after a while into complete paralysis, and may affect the mttsdes of the neck, lips, pharynx, and tongue; no constant derangement of the various forms of cutaneous sensibility; attended with tremor in the disordered musdts, happening only when any voluntary movement is made or attempted, and ceasing whilst the muscles are at rest; often nystagmus; later on cramps, spasms, and permanent contractions of the palsied limbs; of probable diathetic origin; progressive in its course; of fatal ending; the anatomical characters being patches or corns of sclerosis irregtilarly scattered in the white substance of the brain, and in the anterior and lateral columns of the spinal by G-ermnn writers. When the leaders mentioned color above are asked about these other than German products they practically advise against their use.
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